Tapentadol is a prescription pain medication that belongs to the class of opioid analgesics. It is used to treat moderate to severe pain and works by binding to opioid receptors in the brain and spinal cord, reducing the perception of pain. Tapentadol also inhibits the reuptake of norepinephrine, which enhances its pain-relieving effects. Tapentadol Used for the management of acute pain, chronic pain (including neuropathic pain), and in some cases, pain related to conditions like osteoarthritis.