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A synthetic opioid analgesic used to treat moderate to severe pain is called tramadol. It is frequently prescribed for ailments like chronic pain, post-surgical pain, and injury-related pain. Like other opioids, tramadol acts on opioid receptors in the brain, but it also affects neurotransmitters like norepinephrine and serotonin. Pain relief with tramadol is beneficial for both acute and chronic pain disorders. Despite being thought to have a lower risk than other opioids, tramadol is categorized as a Schedule IV prohibited narcotic in the United States because of its potential for misuse and dependency.

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