Get 10% Discount Apply Coupon Code "USA10" The main indication for using Tramadol, a centrally acting analgesic, is moderate to moderately severe pain. It is categorized as an opioid analgesic and acts by attaching itself to brain mu-opioid receptors and preventing serotonin and norepinephrine from being reabsorbed, which helps to regulate pain signals. There are several different formulations of tramadol that are available, such as oral disintegrating pills, extended-release tablets, and immediate-release tablets. Additionally, it could be offered in combination with other drugs like acetaminophen.