Get 10% Discount Apply Coupon Code "USA10" Tramadol is one of the synthetic opioid analgesics used to treat moderate to severe pain. It functions by binding to opioid receptors in the brain, just like other opioids, but it also has additional ways of working that all contribute to pain relief. Tramadol is often used for the treatment of back pain, joint pain, and post-surgical pain. Tramadol has a unique property that may help explain some of its analgesic effects: in addition to acting on opioid receptors, it also increases brain levels of neurotransmitters like norepinephrine and serotonin. It differs from other opioids due to its dual method of action.