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Constipation, nausea, dizziness, vomiting, and drowsiness are common tapentadol side effects. Notifying your healthcare practitioner of any unusual or severe side effects is crucial. When treating moderate to severe acute pain, such as that following surgery or from diseases like osteoarthritis or diabetic neuropathy, tapentadol is typically recommended. Contrary to conventional opioids, tapentadol functions through two different pathways. It blocks norepinephrine's reuptake in addition to acting on opioid receptors. Compared to some other opioids, it may have less side effects due to its dual action, which is thought to contribute to its analgesic effects.
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