Order Lortab Online with FedEx Overnight Delivery. Lortab is a prescription medication that combines hydrocodone, an opioid pain reliever, with acetaminophen. It is commonly used for the short-term management of moderate to moderately severe pain. The hydrocodone component provides effective pain relief by acting on the central nervous system, while acetaminophen enhances its effects. It is important to use Lortab as directed by a healthcare professional, as it carries potential risks and side effects associated with opioid medications. Regular monitoring and adherence to prescribed dosages are crucial for safe and effective use.