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Tramadol is frequently given to treat a variety of pain disorders, including musculoskeletal pain, chronic illnesses linked to mild to moderately severe pain, and pain following surgery. One prescription medicine in the family of medications known as opioid analgesics is tramadol. It is applied to pain ranging from mild to moderately severe. Tramadol functions by attaching itself to mu-opioid receptors in the brain and preventing serotonin and norepinephrine—two neurotransmitters involved in pain perception—from being reabsorbed.

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