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If you take methadone for pain: Take the missed dose as soon as you remember, then take your next dose 8 to 12 hours later.
If you take methadone for drug addiction: Take your missed dose the next day at the regular time. If you miss your doses for longer than 3 days in a row, call your doctor for instructions. You may need to restart your dosing schedule at a lower dose.
Do not take two doses at one time.
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Grapefruit may interact with this medicine and cause side effects. Avoid consuming grapefruit products.
There are many dangerous drug interactions with methadone. Tell your prescribing doctor about all medications that you take. See “What other drugs will affect methadone?” section below.
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